Best of

Best pharmacies in the West Loop, Chicago.

The West Loop carries two CVS locations, five Walgreens, an independent pharmacy on West Jackson, and pharmacy counters inside the Mariano's and Jewel-Osco supermarkets. Each listing below links through to the full business page with address, license record, and (where verified) hours.

CVS

Two CVS Pharmacy locations inside the West Loop, including the in-Target counter.

Walgreens

Five Walgreens locations serving different parts of the neighborhood.

Independent and in-store

A locally-licensed independent and the grocery-store pharmacy counters.

Frequently asked questions

Where is the closest pharmacy to me in the West Loop?
Coverage is dense — CVS and Walgreens both have multiple locations and the central neighborhood is rarely more than a few blocks from one. Walgreens at 1051 W Randolph is the most-central pickup for Restaurant Row addresses; CVS at 1101 W Jackson (inside the Target store) serves the southern Fulton Market and Skinner West school area.
Is there a 24-hour pharmacy in the West Loop?
No West Loop pharmacy currently operates 24 hours. Most locations close between 8 PM and midnight. Confirm hours on each individual location's page before going.
Does the West Loop Target have a pharmacy?
Yes — the CVS Pharmacy counter inside the Target store at 1101 W Jackson Blvd operates as a full CVS location. Prescriptions filed at any CVS are available for pickup here.
Are there independent pharmacies in the West Loop?
CPU RX at 1016 W Jackson is the licensed independent pharmacy serving the central West Loop. The grocery-store pharmacy counters at Mariano's (40 S Halsted) and Jewel-Osco (1340 S Canal) also fill prescriptions.
Do the grocery stores have pharmacies?
Yes. Mariano's Fresh Market at 40 S Halsted and Jewel-Osco at 1340 S Canal both operate on-site pharmacy counters under their parent chains (Kroger/Roundy's and Albertsons respectively). Hours follow grocery hours, not standalone-pharmacy hours.
Where can I get a vaccine in the West Loop?
Most West Loop Walgreens and CVS locations offer flu, COVID-19, and other routine vaccinations. Walk-ins are typically accepted; appointments via each chain's app are faster. The grocery-store pharmacies at Mariano's and Jewel-Osco also offer vaccinations.