Best of
Best pharmacies in the West Loop, Chicago
The West Loop carries two CVS locations, five Walgreens, an independent pharmacy on West Jackson, and pharmacy counters inside the Mariano's and Jewel-Osco supermarkets. Each listing below links through to the full business page with address, license record, and (where verified) hours.
CVS
Two CVS Pharmacy locations inside the West Loop, including the in-Target counter.
- CVS Pharmacy CVS Pharmacy at 1101 W Jackson — the in-Target counter at the West Loop Target store on West Jackson at May.1101 W Jackson Blvd 1st, Chicago, IL, 60607 Call
- CVS Pharmacy Open now CVS/Pharmacy at 1034 W Lake, on the Restaurant Row corridor near Carpenter.1034 W Lake St 1, Chicago, IL, 60607 Call
Walgreens
Five Walgreens locations serving different parts of the neighborhood.
- Walgreens #21160 Open now Walgreens at 1051 W Randolph — central on Restaurant Row.1051 W Randolph St 1, Chicago, IL, 60607 Call
- Walgreens # 04978 Open now Walgreens at 111 S Halsted — at the Greektown corner near Mariano's.111 S Halsted St First, Chicago, IL, 60661 Call
- Walgreens #21221 Walgreens at 433 W Van Buren — south end of the neighborhood near the Van Buren / Canal Metra connector.433 W Van Buren St 150, Chicago, IL, 60607 Call
- Walgreens #04461 Open now Walgreens at 501 W Roosevelt — on the Roosevelt corridor at the south edge of the West Loop.501 W Roosevelt Rd, Chicago, IL, 60607Near the West Loop Call
- Walgreens # 03961 Open now Walgreens at 2340 W Madison — west edge of the neighborhood approaching United Center.2340 W Madison St, Chicago, IL, 60612Near the West Loop Call
Independent and in-store
Locally-licensed independents and the grocery-store pharmacy counters.
- Cpu Rx CPU RX at 1016 W Jackson — independent pharmacy serving the central West Loop.1016 W Jackson Blvd 110, Chicago, IL, 60607 Call
- West Loop Pharmacy Open now West Loop Pharmacy at 932 W Washington Blvd (Ste 100) — community-focused independent pharmacy with an emphasis on preventive health, patient communication, and accessibility. Weekday hours.
Frequently asked questions
- Where is the closest pharmacy to me in the West Loop?
- Coverage is dense — CVS and Walgreens both have multiple locations and the central neighborhood is rarely more than a few blocks from one. Walgreens at 1051 W Randolph is the most-central pickup for Restaurant Row addresses; CVS at 1101 W Jackson (inside the Target store) serves the southern Fulton Market and Skinner West school area.
- Is there a 24-hour pharmacy in the West Loop?
- No West Loop pharmacy currently operates 24 hours. Most locations close between 8 PM and midnight. Confirm hours on each individual location's page before going.
- Does the West Loop Target have a pharmacy?
- Yes — the CVS Pharmacy counter inside the Target store at 1101 W Jackson Blvd operates as a full CVS location. Prescriptions filed at any CVS are available for pickup here.
- Are there independent pharmacies in the West Loop?
- CPU RX at 1016 W Jackson is the licensed independent pharmacy serving the central West Loop. The grocery-store pharmacy counters at Mariano's (40 S Halsted) and Jewel-Osco (1340 S Canal) also fill prescriptions.
- Do the grocery stores have pharmacies?
- Yes. Mariano's Fresh Market at 40 S Halsted and Jewel-Osco at 1340 S Canal both operate on-site pharmacy counters under their parent chains (Kroger/Roundy's and Albertsons respectively). Hours follow grocery hours, not standalone-pharmacy hours.
- Where can I get a vaccine in the West Loop?
- Most West Loop Walgreens and CVS locations offer flu, COVID-19, and other routine vaccinations. Walk-ins are typically accepted; appointments via each chain's app are faster. The grocery-store pharmacies at Mariano's and Jewel-Osco also offer vaccinations.
Most recent pick verified 5 days ago. Some picks may be older — the date reflects whichever pick on this page was checked most recently.